BDBM488579 US10961198, Compound 2.04::trans-N-((trans-4-(3-Cyano-4- methoxyphenyl)cyclohexyl)methyl)-N-(3-(1-cyclopropyl- 1H-pyrazol-4-yl)phenyl)-4- hydroxycyclohexanecarboxamide

SMILES COc1ccc(cc1C#N)[C@H]1CC[C@H](CN(C(=O)[C@H]2CC[C@H](O)CC2)c2cccc(c2)-c2cnn(c2)C2CC2)CC1

InChI Key InChIKey=GVRKIZUWIWTNQJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488579   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488579(US10961198, Compound 2.04 | trans-N-((trans-4-(3-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent