BDBM488584 US10961198, Compound 2.09::trans-4-Hydroxy-N-(4-(1-isopropyl-1H-pyrazol-4- yl)pyridin-2-yl)-N-(4-(4-methoxy-3- methylphenyl)bicyclo[2.2.2]octan-1- yl)methyl)cyclohexanecarboxamide

SMILES COc1ccc(cc1C)C12CCC(CN(C(=O)[C@H]3CC[C@H](O)CC3)c3cc(ccn3)-c3cnn(c3)C(C)C)(CC1)CC2

InChI Key InChIKey=IIOFNPDZKSMAFK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488584   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488584(US10961198, Compound 2.09 | trans-4-Hydroxy-N-(4-(...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent