BDBM488597 US10961198, Compound 3.12::trans-N-(3-(1-(2-Fluoroethyl)-1H-pyrazol-4-yl)phenyl)-4- hydroxy-N-((trans-4-(4-methoxy-3- methylphenyl)cyclohexyl)methyl)cyclohexanecarboxamide

SMILES COc1ccc(cc1C)[C@H]1CC[C@H](CN(C(=O)[C@H]2CC[C@H](O)CC2)c2cccc(c2)-c2cnn(CCF)c2)CC1

InChI Key InChIKey=RQGVZAOSCIYLIC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488597   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488597(US10961198, Compound 3.12 | trans-N-(3-(1-(2-Fluor...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent