BDBM488607 US10961198, Compound 5.04::trans-N-(3-(1-cyclopropyl-1H-pyrazol-4-yl)phenyl)-4- hydroxy-N-((trans-4-(5-methoxy-6-methylpyridin-2- yl)cyclohexyl)methyl)cyclohexanecarboxamide

SMILES COc1ccc(nc1C)[C@H]1CC[C@H](CN(C(=O)[C@H]2CC[C@H](O)CC2)c2cccc(c2)-c2cnn(c2)C2CC2)CC1

InChI Key InChIKey=IQGAFHMDESVUTC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488607   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488607(US10961198, Compound 5.04 | trans-N-(3-(1-cyclopro...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent