BDBM488633 US10961198, Compound 5.30::trans-N-((trans-4-(5-Chloro-6-methoxypyridin-3- yl)cyclohexyl)methyl)-4-hydroxy-N-(4-(1-isopropyl-1H- pyrazol-4-yl)pyridin-2-yl)cyclohexanecarboxamide

SMILES COc1ncc(cc1Cl)[C@H]1CC[C@H](CN(C(=O)[C@H]2CC[C@H](O)CC2)c2cc(ccn2)-c2cnn(c2)C(C)C)CC1

InChI Key InChIKey=LASSLZULRSPVHE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488633   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488633(US10961198, Compound 5.30 | trans-N-((trans-4-(5-C...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent