BDBM488634 US10961198, Compound 6::trans-N-(3-(1-Cyclopropyl-1H-pyrazol-4-yl)phenyl)-4-hydroxy-N-((4-(4-methoxy-3-methylphenyl)bicyclo[2.2.2]octan-1-yl)methyl)cyclohexanecarboxamide

SMILES COc1ccc(cc1C)C12CCC(CN(C(=O)[C@H]3CC[C@H](O)CC3)c3cccc(c3)-c3cnn(c3)C3CC3)(CC1)CC2

InChI Key InChIKey=SNISVWGSLLFYEB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488634   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488634(US10961198, Compound 6 | trans-N-(3-(1-Cyclopropyl...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent