BDBM489154 (E)-2-(3-(3-(2- cyclopentylvinyl)-4- fluorophenyl)-5- (cyclopropylmethyl)- 4-(3-fluoro-4- sulfamoylbenzyl)- 1H-pyrazol-1- yl)thiazole-4- carboxylic acid::US10961200, Compound 535

SMILES N[S+]([O-])(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(\C=C\C3CCCC3)c2)-c2nc(cs2)C(O)=O)cc1F

InChI Key InChIKey=NCDPUVJTMBDUAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 489154   

TargetL-lactate dehydrogenase A chain(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM489154(US10961200, Compound 535 | (E)-2-(3-(3-(2- cyclope...)
Affinity DataIC50: 100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent