BDBM490393 N-(2-chloro-6-methylphenyl)-5-fluoro-4-(3-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide::US10968216, Example 61

SMILES CCc1cccc(Cl)c1NC(=O)c1cc(F)c(cc1O[C@@H](C)C(F)(F)F)-n1nc2CCCCn2c1=O

InChI Key InChIKey=JSHVHNSFRLYVEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490393   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
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US Patent
LigandPNGBDBM490393(US10968216, Example 61 | N-(2-chloro-6-methylpheny...)
Affinity DataIC50: 2nMAssay Description:Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
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Date in BDB:
10/9/2021
Entry Details
US Patent