BDBM490448 2-[(1S)-1-cyclohexylethoxy]-5-fluoro-N-(6-methoxy-4-methylpyridin-3-yl)-4-(3-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)benzamide::US10968216, Example 116

SMILES COc1cc(C)c(NC(=O)c2cc(F)c(cc2O[C@@H](C)C2CCCCC2)-n2nc3CCCCn3c2=O)cn1

InChI Key InChIKey=ALMSXVXZOIWABT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490448   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
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US Patent
LigandPNGBDBM490448(US10968216, Example 116 | 2-[(1S)-1-cyclohexyletho...)
Affinity DataIC50: 3.30nMAssay Description:Assay 1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
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Date in BDB:
10/9/2021
Entry Details
US Patent