BDBM491045 (E)-3-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(pyridin-3-yl-methyleneoxy) benzylamino) but-2-enenitrile::US10975049, Example 14

SMILES C\C(NCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCc1cccnc1)=C/C#N

InChI Key InChIKey=PYHUYSVFQOHZFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491045   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM491045(US10975049, Example 14 | (E)-3-(4-(2-bromo-3-pheny...)
Affinity DataIC50: 2.69E+4nMAssay Description:In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Princip...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent