BDBM492314 US10975081, Example E4

SMILES COc1nc(cc(n1)-n1ncc2cc(C)c(cc12)C1CCN(C)CC1(F)F)N1CCOCC1

InChI Key InChIKey=LOPPRRSSEIXPOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492314   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM492314(US10975081, Example E4)
Affinity DataIC50: 7.94nMAssay Description:1. A 10 mM test compound was dissolved in 100% DMSO and serially diluted 1 in 4. 100 nL of this dilution series was then added to a 384 well, v botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent