BDBM492329 US10975081, Example E38::US10975081, Example E39

SMILES COc1nc(cc(n1)-n1ncc2cc(C)c(cc12)[C@H]1CCN(C)C[C@H]1F)N1CC(O)C1

InChI Key InChIKey=YBKASVSQGWIHND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492329   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM492329(US10975081, Example E38 | US10975081, Example E39)
Affinity DataIC50: 10nMAssay Description:1. A 10 mM test compound was dissolved in 100% DMSO and serially diluted 1 in 4. 100 nL of this dilution series was then added to a 384 well, v botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM492329(US10975081, Example E38 | US10975081, Example E39)
Affinity DataIC50: 10nMAssay Description:1. A 10 mM test compound was dissolved in 100% DMSO and serially diluted 1 in 4. 100 nL of this dilution series was then added to a 384 well, v botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent