BDBM492387 US10975081, Example E66

SMILES COc1nc(cc(n1)-n1ncc2cc(C)c(cc12)C1CCNCC1(F)F)N1CC(C1)C#N

InChI Key InChIKey=JUSWTOQROMMNCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492387   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM492387(US10975081, Example E66)
Affinity DataIC50: 31.6nMAssay Description:1. A 10 mM test compound was dissolved in 100% DMSO and serially diluted 1 in 4. 100 nL of this dilution series was then added to a 384 well, v botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent