BDBM492397 US10975081, Example E239

SMILES Cc1nc(cc(n1)-n1ncc2cc(C)c(cc12)C1CCOCC1)N1CCO[C@@H](CO)C1

InChI Key InChIKey=GTQAJDKSRXRTIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492397   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM492397(US10975081, Example E239)
Affinity DataIC50: 12.6nMAssay Description: LRRKtide Detection settings: Q1 mass 644.8 Da, Q3 mass 638.8, declustering potential 76 volts, collision energy 37 volts, CXP 34 volts Phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent