BDBM493767 US10988455, Example 1(clxxvi)

SMILES Cc1cc(cc(Cl)n1)-c1nnc(N)nc1-c1ccccc1F

InChI Key InChIKey=RJOBHNRSFMJGBB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493767   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM493767(US10988455, Example 1(clxxvi))
Affinity DataKi:  9.33nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM493767(US10988455, Example 1(clxxvi))
Affinity DataKi:  117nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent