BDBM494133 N-[2-(4- hydroxycyclohe xyl)-6- morpholino-1- oxo-isoindolin- 5- yl]pyrazolo[1,5- a]pyrimidine-3- carboxamide::US10988478, Example 181

SMILES O=C(Nc1cc2c(cc1N1CCOCC1)C(=O)N([C@H]1CC[C@H](O)CC1)C2)c1cnn2cccnc12

InChI Key InChIKey=ABFVSZATSGWPOP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494133   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 494133BDBM494133(US10988478, Example 181 | N-[2-(4- hydroxycyclohe ...)
Affinity DataKi:  2nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent