BDBM494544 US10988482, Compound 48::US10988482, Compound 55::US10988482, Compound 64

SMILES C[C@]1(O)CC[C@H](Nc2nc(Nc3cc(C(=O)NC4CCNC4)ns3)nc3ccsc23)CC1

InChI Key InChIKey=KUVJOKCRXXEBHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 494544   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 494544BDBM494544(US10988482, Compound 48 | US10988482, Compound 64 ...)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 494544BDBM494544(US10988482, Compound 48 | US10988482, Compound 64 ...)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 494544BDBM494544(US10988482, Compound 48 | US10988482, Compound 64 ...)
Affinity DataIC50: 550nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent