BDBM494553 US10988482, Compound 57

SMILES C[C@]1(O)CC[C@H](Nc2nc(Nc3cc(C(=O)NC4CCOCC4)ns3)nc3ccsc23)CC1

InChI Key InChIKey=VJZYLTXNPJBIEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494553   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 494553BDBM494553(US10988482, Compound 57)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent