BDBM494878 US10988463, Example 12::US11634410, Example 18

SMILES C[C@H]1[C@H](O)CN1c1nc(N2C[C@H]3[C@H](CC(O)=O)[C@H]3C2)c(Cl)c(n1)C(C)(F)F

InChI Key InChIKey=NGEBOCPTYJZMAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 494878   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM494878(US10988463, Example 12 | US11634410, Example 18)
Affinity DataIC50: 16.7nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM494878(US10988463, Example 12 | US11634410, Example 18)
Affinity DataIC50: 289nMAssay Description:Assay A, a 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent