BDBM497365 US11739077, Example 21

SMILES CC(C)n1cc(nc1-c1ccc(nc1)N1CCc2c(C1)c(nn2C)-c1c(O)ncnc1C1CC1)C(F)(F)F

InChI Key InChIKey=LUOOWRLHZJSMQH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497365   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM497365(US11739077, Example 21)
Affinity DataIC50: 5.50E+3nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2023
Entry Details
US Patent