BDBM498262 US11014911, Example 87::US11014911, Example 88::US11718603, Example 88

SMILES COCCn1nccc1C(=O)Nc1cc([nH]n1)[C@H]1CC[C@H](C1)OC(=O)NC(C)CC(F)(F)F

InChI Key InChIKey=NPWCVESPLJONCX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 498262   

LigandPNGBDBM498262(US11014911, Example 88 | US11014911, Example 87 | ...)
Affinity DataKi:  0.150nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

LigandPNGBDBM498262(US11014911, Example 88 | US11014911, Example 87 | ...)
Affinity DataKi:  0.150nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498262(US11014911, Example 88 | US11014911, Example 87 | ...)
Affinity DataKi:  1.32nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498262(US11014911, Example 88 | US11014911, Example 87 | ...)
Affinity DataKi:  1.32nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent