BDBM499242 US11014963, Example 141

SMILES COc1ccc(cc1)[C@H](NC(=O)[C@H](C)NC(=O)C(C(C)C)c1ccc(Cl)cc1)C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=AOBZLOCDOSIEAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499242   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM499242(US11014963, Example 141)
Affinity DataIC50: 1.80nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent