BDBM499276 US11014963, Example 181

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)C(F)(F)c1cccc(Cl)c1)c1ccc(OCC(=O)OC(C)(C)C)cc1)C(=O)C(F)(F)F

InChI Key InChIKey=GOJCMRDSQICSDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499276   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM499276(US11014963, Example 181)
Affinity DataIC50: 2nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent