BDBM50000056 (sulmazole)2-(4-Methanesulfinyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine::2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine::2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine (sulmazole)::2-(4-Methanesulfinyl-2-methoxy-phenyl)-1H-imidazo[4,5-b]pyridine(sulmazole)::2-(4-Methanesulfinyl-2-methoxy-phenyl)-3H-imidazo[4,5-b]pyridine::2-Methyl-6-oxo-1,6-dihydro-[3,4']bipyridinyl-5-carbonitrile::CHEMBL286020

SMILES COc1cc(ccc1-c1nc2ncccc2[nH]1)S(C)=O

InChI Key InChIKey=XMFCOYRWYYXZMY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50000056   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000056(CHEMBL286020 | 2-(4-Methanesulfinyl-2-methoxy-phen...)
Affinity DataIC50: 2.10E+4nMAssay Description:In vitro inhibition of PDE-V isolated from porcine pulmonary artery.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50000056(CHEMBL286020 | 2-(4-Methanesulfinyl-2-methoxy-phen...)
Affinity DataIC50: 5.01E+4nMAssay Description:Concentration of compound required for 50% inhibition of type III cAMP phosphodiesterase from dog ventricles, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2018
Entry Details

LigandPNGBDBM50000056(CHEMBL286020 | 2-(4-Methanesulfinyl-2-methoxy-phen...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of PDE 3 (phosphodiesterase III) from guinea pig ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50000056(CHEMBL286020 | 2-(4-Methanesulfinyl-2-methoxy-phen...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclic GMP sensitive phosphodiesterase PDE 2 of guinea pig ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50000056(CHEMBL286020 | 2-(4-Methanesulfinyl-2-methoxy-phen...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50000056(CHEMBL286020 | 2-(4-Methanesulfinyl-2-methoxy-phen...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed