BDBM50000177 7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene::CHEMBL301605

SMILES c1ccc2c(c1)[nH]c1cnc3c4ccccc4[nH]c3c21

InChI Key InChIKey=UFTKNTUWDMJOIX-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50000177   

LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human recombinant GABAA alpha3 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human recombinant GABAA alpha2 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human recombinant GABAA alpha1 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  40nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi:  40nMAssay Description:Binding affinity to human recombinant GABAA alpha5 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-6-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000177(7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene |...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human recombinant GABAA alpha6 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed