BDBM50002002 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12186

SMILES Fc1ccc(cc1)-n1cc(C2=CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12

InChI Key InChIKey=PFOLMILRZUSKJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002002   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002002(CHEMBL12186 | 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl...)
Affinity DataIC50: 2.30nMAssay Description:Compound was tested for the inhibition of [3H]spiperone binding to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002002(CHEMBL12186 | 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002002(CHEMBL12186 | 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed