BDBM50002015 5-Chloro-1-(4-fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL12507

SMILES CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key InChIKey=VMZWFUNEODYUEN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002015   

TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002015(CHEMBL12507 | 5-Chloro-1-(4-fluoro-phenyl)-3-(1-me...)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of [3H]ketanserin binding to dopamine 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002015(CHEMBL12507 | 5-Chloro-1-(4-fluoro-phenyl)-3-(1-me...)
Affinity DataIC50: 1.10nMAssay Description:Compound was tested for the inhibition of [3H]spiperone binding to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002015(CHEMBL12507 | 5-Chloro-1-(4-fluoro-phenyl)-3-(1-me...)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity towardst dopamine D2 receptor by displacement of [3H]-SPI radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50002015(CHEMBL12507 | 5-Chloro-1-(4-fluoro-phenyl)-3-(1-me...)
Affinity DataIC50: 9.80nMAssay Description:Binding affinity towards dopamine receptor D1 by displacement of [3H]-SCH- radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed