BDBM50002242 2-{1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-4-yl}-1-(4-fluoro-phenyl)-ethanone::CHEMBL139963

SMILES Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccc(Cl)cc2)CC1

InChI Key InChIKey=IHZMBRPMQIFTMC-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002242   

TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002242(2-{1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-4-yl}-1...)
Affinity DataKi:  5nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mus musculus (Mouse))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002242(2-{1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-4-yl}-1...)
Affinity DataKi:  8.40nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Mus musculus (Mouse))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002242(2-{1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-4-yl}-1...)
Affinity DataIC50:  14nMAssay Description:In vitro binding affinity towards dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed