BDBM50004346 CHEMBL3237848

SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(Nc2nnc3n(C)nc(C)c3n2)cc1

InChI Key InChIKey=NZWBYPUCGPIPHB-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50004346   

TargetCarbonic anhydrase 12(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50004346(CHEMBL3237848)
Affinity DataKi:  5.30nMAssay Description:Inhibition of human carbonic anhydrase 12-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50004346(CHEMBL3237848)
Affinity DataKi:  667nMAssay Description:Inhibition of human carbonic anhydrase 2-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50004346(CHEMBL3237848)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 9-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50004346(CHEMBL3237848)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in Sf9 cells using histone H1 as substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50004346(CHEMBL3237848)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50004346(CHEMBL3237848)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Abl kinase (unknown origin) expressed in Sf9 cells using GGEAIYAAPFKK as substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50004346(CHEMBL3237848)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CK2alpha1 (unknown origin) using casein as substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed