BDBM50004418 CHEMBL3238163

SMILES CN(C)CC(O)CN1CCN(CC1)c1nc(cnc1N1CCCC1)-c1ccncc1

InChI Key InChIKey=XJBTVKIGCWNSPP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004418   

TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004418(CHEMBL3238163)
Affinity DataIC50: 76nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004418(CHEMBL3238163)
Affinity DataIC50: 288nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004418(CHEMBL3238163)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed