BDBM50004673 CHEMBL104355::[2-(5-Dimethylaminomethyl-furan-2-ylmethylsulfanyl)-ethyl]-(4-fluoro-2-nitro-phenyl)-amine

SMILES CN(C)Cc1ccc(CSCCNc2ccc(F)cc2[N+]([O-])=O)o1

InChI Key InChIKey=NEZXWTGSAGKVIL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50004673   

TargetAcetylcholinesterase(Homo sapiens (Human))
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004673(CHEMBL104355 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50:  650nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Mus musculus)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004673(CHEMBL104355 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of [3H]-pirenzepine binding to mouse muscarinic acetylcholine receptor M1 from cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004673(CHEMBL104355 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of [3H]-N-methylscopolamine to rat muscarinic acetylcholine receptor M2 from heart tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004673(CHEMBL104355 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibition of human butryl cholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed