BDBM50005005 CHEMBL2397317

SMILES COc1ccc(cc1OC)-c1c(C)nn2c(NCCN3CCOCC3)cc(C)nc12

InChI Key InChIKey=RITGMCAEZVMEQO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50005005   

TargetPhosphatidylinositol 4-kinase beta(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50005005(CHEMBL2397317)
Affinity DataIC50:  137nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50005005(CHEMBL2397317)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50005005(CHEMBL2397317)
Affinity DataIC50:  60nMAssay Description:Inhibition of PI4K3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50005005(CHEMBL2397317)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase beta(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50005005(CHEMBL2397317)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50005005(CHEMBL2397317)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PI4K2alpha (unknown origin) assessed as hydrolysis of ATP for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed