BDBM50005786 CHEMBL3235854

SMILES COc1ccc(C(=O)N2CCc3nc(ncc3C2)N2CCN(CC2)c2ncccn2)c(OC)c1

InChI Key InChIKey=KFUDFRIRWRPGHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005786   

TargetHeat shock protein HSP 90-beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005786(CHEMBL3235854)
Affinity DataIC50: 7.88E+3nMAssay Description:Inhibition of full-length HSP90 (unknown origin) expressed in Escherichia coli assessed as inhibition of ATPase activity after 3 hrs by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005786(CHEMBL3235854)
Affinity DataIC50: 3.05E+4nMAssay Description:Displacement of FITC-geldanamycin from HSP90 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed