BDBM50005790 CHEMBL3235858

SMILES Cc1ncc2CN(CCc2n1)C(=O)c1cc(Cl)c(O)cc1O

InChI Key InChIKey=OIYQOJBOWPOPMU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005790   

TargetHeat shock protein HSP 90-beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005790(CHEMBL3235858)
Affinity DataIC50: 100nMAssay Description:Displacement of FITC-geldanamycin from HSP90 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005790(CHEMBL3235858)
Affinity DataIC50: 101nMAssay Description:Displacement of FITC-geldanamycin from N-terminal HSP90alpha (unknown origin) after 30 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005790(CHEMBL3235858)
Affinity DataIC50: 420nMAssay Description:Inhibition of full-length HSP90 (unknown origin) expressed in Escherichia coli assessed as inhibition of ATPase activity after 3 hrs by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed