BDBM50006115 (R)-RETRO-THIORPHAN::(RETRO)N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic acid::(S) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic acid::CHEMBL45412

SMILES OC(=O)CC(=O)N[C@@H](CS)Cc1ccccc1

InChI Key InChIKey=REPVVNYZORKKPQ-SNVBAGLBSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006115   

TargetNeprilysin(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50006115((R)-RETRO-THIORPHAN | (RETRO)N-(1-Mercaptomethyl-2...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of NEP 24.11 (unknown origin) by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50006115((R)-RETRO-THIORPHAN | (RETRO)N-(1-Mercaptomethyl-2...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50006115((R)-RETRO-THIORPHAN | (RETRO)N-(1-Mercaptomethyl-2...)
Affinity DataIC50:  1.00E+9nMAssay Description:Inhibition of angiotensin I converting enzyme in silicoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50006115((R)-RETRO-THIORPHAN | (RETRO)N-(1-Mercaptomethyl-2...)
Affinity DataIC50:  210nMAssay Description:Concentration for 50% inhibition of activity of rat kidney enkephalinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed