BDBM50007458 1-[4-(9-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone::CHEMBL143272

SMILES CC(=O)N1CCC(=C2c3cc(F)ccc3CCc3cccnc32)CC1

InChI Key InChIKey=VYKKZLFRKROXFD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007458   

TargetPlatelet-activating factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007458BDBM50007458(CHEMBL143272 | 1-[4-(9-Fluoro-5,6-dihydro-benzo[5,...)
Affinity DataIC50: 820nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007458BDBM50007458(CHEMBL143272 | 1-[4-(9-Fluoro-5,6-dihydro-benzo[5,...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed