BDBM50007464 4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-carbaldehyde::CHEMBL325909

SMILES O=CN1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1

InChI Key InChIKey=BBXUSMHUBCXTCF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007464   

TargetHistamine H1 receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007464BDBM50007464(CHEMBL325909 | 4-(8-Chloro-5,6-dihydro-benzo[5,6]c...)
Affinity DataKi:  21nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007464BDBM50007464(CHEMBL325909 | 4-(8-Chloro-5,6-dihydro-benzo[5,6]c...)
Affinity DataIC50: 1.30E+4nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed