BDBM50007559 5-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-1,3-dihydro-indol-2-one::CHEMBL54786

SMILES O=C1Cc2cc(CCN3CCN(CC3)c3cccc4ccccc34)ccc2N1

InChI Key InChIKey=GEJKYGSJUJTWOZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50007559   

Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 4.87nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 38nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 44nMAssay Description:Inhibition constant against dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 45nMAssay Description:Inhibitory concentration against alpha adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed