BDBM50008122 5-Cyclohexyl-2,2-difluoro-4-{2-[2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoylamino}-3-oxo-pentanoic acid ethyl ester; C13H24N2O::CHEMBL31679

SMILES CCOC(=O)C(F)(F)C(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC=C)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1

InChI Key InChIKey=AEIQMTCHERRLBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008122   

TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008122(CHEMBL31679 | 5-Cyclohexyl-2,2-difluoro-4-{2-[2-(m...)
Affinity DataIC50: 0.400nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008122(CHEMBL31679 | 5-Cyclohexyl-2,2-difluoro-4-{2-[2-(m...)
Affinity DataIC50: 69nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed