BDBM50009217 CHEMBL3233184

SMILES CCS(=O)(=O)C[C@@H]1C[C@@H](CC[C@@H]1N1CC[C@H](NC(=O)c2cccc(c2)C(F)(F)F)C1=O)N(C)C(C)C

InChI Key InChIKey=VPQJUCNKBPHRCP-FKVLARQCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009217   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50009217(CHEMBL3233184)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]-labeled human MCP1 from CCR2 in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50009217(CHEMBL3233184)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as reduction of chemotaxis in presence of 0.1 M BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50009217(CHEMBL3233184)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed