BDBM50009768 (7-Chloro-3-naphtho[1,2-d]thiazol-2-ylmethyl-4-oxo-3,4-dihydro-phthalazin-1-yl)-acetic acid::CHEMBL2079662::CHEMBL279275

SMILES OC(=O)Cc1nn(Cc2nc3c(ccc4ccccc34)s2)c(=O)c2ccc(Cl)cc12

InChI Key InChIKey=QNAYWPPENIEFMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009768   

TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009768BDBM50009768(CHEMBL279275 | CHEMBL2079662 | (7-Chloro-3-naphtho...)
Affinity DataIC50: 300nMAssay Description:Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009768BDBM50009768(CHEMBL279275 | CHEMBL2079662 | (7-Chloro-3-naphtho...)
Affinity DataIC50: 350nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed