BDBM50010239 CHEMBL1236538

SMILES O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)cc1Cl

InChI Key InChIKey=RBQXEHDSKLSKLJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50010239   

TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010239BDBM50010239(CHEMBL1236538)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010239BDBM50010239(CHEMBL1236538)
Affinity DataKi:  190nMAssay Description:Inhibition of amethopterin-resistant Lactobacillus casei thymidylate synthetase-catalyzed dTMP formation using dUMP as substrate by spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010239BDBM50010239(CHEMBL1236538)
Affinity DataKi:  200nMAssay Description:The compound was evaluated for the inhibition of dTMP synthetase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010239BDBM50010239(CHEMBL1236538)
Affinity DataKi:  9.39E+3nMAssay Description:Inhibition of amethopterin-resistant Lactobacillus casei thymidylate synthetase-catalyzed 5-BrdUMP dehalogenation by absorbance analysis in absence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed