BDBM50011510 CHEMBL3261918

SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccccc1)C#N)[C@@H]1CCCCN1

InChI Key InChIKey=AGQMDQHFBCAQCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011510   

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50011510(CHEMBL3261918)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human cathepsin C using H-Gly-Arg-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50011510(CHEMBL3261918)
Affinity DataIC50: 158nMAssay Description:Inhibition of cathepsin C in human THP1 cells assessed as inhibition of H-Gly-Phe-AFC cleavage by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed