BDBM50011553 CHEMBL3262572::US9592235, Example 167::US9855269, Compound 10

SMILES COc1cccc(c1)-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=HAFNABUNLVCDOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011553   

LigandPNGBDBM50011553(CHEMBL3262572 | US9592235, Example 167 | US9855269...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
LigandPNGBDBM50011553(CHEMBL3262572 | US9592235, Example 167 | US9855269...)
Affinity DataIC50: 591nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011553(CHEMBL3262572 | US9592235, Example 167 | US9855269...)
Affinity DataIC50: 591nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent