BDBM50011789 CHEMBL3262931::US10287279, Compound 39

SMILES CNc1nc(ccc1C#N)-c1cccc2ccccc12

InChI Key InChIKey=SZVANFJEISJUEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011789   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
The Children'S Hospital

US Patent
LigandPNGBDBM50011789(CHEMBL3262931 | US10287279, Compound 39)
Affinity DataIC50: 4.00E+4nMAssay Description:The inhibitor compounds were screened initially using one concentration point on a Perkin-Elmer Lambda 40 UV-Vis spectrometer. The percent inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
The Children'S Hospital

US Patent
LigandPNGBDBM50011789(CHEMBL3262931 | US10287279, Compound 39)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed