BDBM50013074 2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one::2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one(BuPG)::CHEMBL16193

SMILES CCCCc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1

InChI Key InChIKey=OPAPDEANGWQVRT-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50013074   

LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)
Affinity DataKi:  7.50E+3nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)
Affinity DataKi:  1.20E+4nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThymidine kinase(HHV-1)
Istituto Di Genetica Biochimica Ed Evoluzionistica

Curated by ChEMBL
LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of [3H]-MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThymidine kinase(HHV-2)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThymidine kinase(HHV-1)
Istituto Di Genetica Biochimica Ed Evoluzionistica

Curated by ChEMBL
LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThymidine kinase(HHV-1)
Istituto Di Genetica Biochimica Ed Evoluzionistica

Curated by ChEMBL
LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibitory activity against HSV-1 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThymidine kinase(HHV-1)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed