BDBM50013212 CHEMBL160102::Sodium salt of7-[4-(4-Fluoro-phenyl)-1,2-diisopropyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid
SMILES CC(C)c1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1C(C)C)-c1ccc(F)cc1
InChI Key InChIKey=JNPGUXGVLNJQSQ-BGGMYYEUSA-M
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50013212
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of cellular HMG-CoA reductase in cultures of hepatic cells (HEP G2, a human hepatoma cell line)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst
Curated by ChEMBL
Hoechst
Curated by ChEMBL
Affinity DataIC50: 117nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair