BDBM50013885 CHEMBL3260035

SMILES COc1c(SCC(O)=O)cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc12

InChI Key InChIKey=GKYKQIMOHSMRSO-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50013885   

TargetBcl-2-related protein A1(Human)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50013885(CHEMBL3260035)
Affinity DataKi:  3.23E+3nMAssay Description:Inhibition of Bfl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50013885(CHEMBL3260035)
Affinity DataKi:  8.64E+3nMAssay Description:Inhibition of Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50013885(CHEMBL3260035)
Affinity DataKi:  8.70E+4nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
LigandPNGBDBM50013885(CHEMBL3260035)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed