BDBM50013909 CHEMBL3260505

SMILES CCc1cnc(nc1)N1CCC(CC1)c1nc(COc2ccc(cc2)-n2cnnn2)cs1

InChI Key InChIKey=NFTMKHWBOINJGM-UHFFFAOYSA-N

Data  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013909   

TargetGlucose-dependent insulinotropic receptor(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50013909(CHEMBL3260505)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human GPR119 overexpressed in CHO cells assessed as stimulation of cAMP production by HTRF assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50013909(CHEMBL3260505)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at GPR119 (unknown origin) assessed as increase in cAMP level by cAMP HTRF assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50013909(CHEMBL3260505)
Affinity DataEC50:  87nMAssay Description:Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair