BDBM50014048 CHEMBL41303::{1-[1-[1-Cyclohexylmethyl-2-hydroxy-2-(4-methylene-5-oxo-tetrahydro-furan-2-yl)-ethylcarbamoyl]-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H]1CC(=C)C(=O)O1

InChI Key InChIKey=SOWSWTQQDMLKKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014048   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014048(CHEMBL41303 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 0.710nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014048(CHEMBL41303 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed